The Symptoms of Acromegaly

Acromegaly can cause many different symptoms related to the pituitary tumor and the extra growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in your body. These symptoms can cause the physical changes seen with acromegaly and changes to your general health.

Because there are a variety of acromegaly symptoms, it can often take a long time to be diagnosed. The symptoms may be confused with those caused by more common conditions.

Common Acromegaly Signs and Symptoms
Tumor-related
  • Headaches
  • Vision problems
  • Seizures
  • Impotence (men)
  • Changes to the menstrual cycle (women)
Hormone-related (extra GH and IGF-1)
  • Enlarged hands, feet, nose, ears, and tongue
  • Skin changes (thickening, oily, skin tags)
  • Excessive sweating
  • Joint pains
  • Snoring
  • Sleep apnea (ie, breathing stops and starts during sleep)
  • Tiredness and weakness
  • More prominent jaw and forehead
  • Pain, tingling, and/or weakness in the hands (carpal tunnel syndrome)
  • Thyroid problems (tiredness, weight change, hair loss, sweating, swollen neck, feeling cold)
  • Decreased libido
Acromegaly symptoms can change over time. Keep track of any changes you experience, and share them with your doctor. This important information can help your doctor manage your condition.